Diclobene retard : Uses, Dosage, Side Effects

Diclobene retard, a brand name for a formulation containing essential Diclofenac, is widely used for various health benefits. This guide provides comprehensive information on the uses, dosage, side effects, and mechanism of action of Diclobene retard, as well as insights into how long it takes to work. Understanding these aspects can help you make informed decisions about its use and effectiveness.

Introduction

Diclobene retard is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking the production of certain natural substances that cause inflammation. Diclobene retard is used to treat pain and inflammation associated with various conditions, including arthritis, muscle sprains and strains, gout, painful menstrual periods, and migraine.

Uses

Diclobene retard is used to treat pain and inflammation associated with various conditions, including arthritis, muscle sprains and strains, gout, painful menstrual periods, and migraine.

Mechanism of Action

Diclobene retard works by blocking the production of certain natural substances that cause inflammation.

Absorption

Diclobene retard is absorbed rapidly and extensively with oral administration.

Route of Elimination

Diclobene retard is mainly eliminated by metabolism in the liver and to a small extent by excretion through the kidney.

Dosage

The recommended dose of diclofenac is 50-100mg, up to three times a day, depending on the condition and individual response. It is generally taken with food or milk to reduce stomach irritation.

Administration

Diclobene retard is available in various forms, including tablets, capsules, and topical gels, or liquid. It is generally taken by mouth with or without food.

Side Effects

Common side effects of diclofenac include nausea, vomiting, stomach upset, headache, dizziness, and drowsiness. Other more serious side-effects include an increased risk of stroke, heart attack, bleeding, and ulcers.

Toxicity

The onset of toxicity is usually at the 75mg dose. Symptoms may include drowsiness, confusion, dizziness, and nausea.

Precaution

Patients should not take diclofenac if they have a history of ulcers, or if they are taking other medications that may increase the risk of bleeding, such as warfarin, aspirin, or any other NSAIDs. In addition, it should be used with caution in patients with high blood pressure, kidney or liver disease, or heart failure.

Interaction

Diclobene retard should not be used with certain medications, including corticosteroids, diuretics, and warfarin. In addition, patients should avoid alcohol, as it can increase the risk of stomach irritation.

Disease Interaction

Diclobene retard should not be used in patients with certain diseases. These include stomach, kidney, or liver diseases, as well as bleeding disorders or heart failure.

Drug Interaction

Diclobene retard may interact with other medications, including antacids, lithium, and warfarin. Patients should talk to their doctor about any medications they are taking before beginning treatment with diclofenac.

Food Interactions

Diclobene retard should not be taken with food. Patients should make sure to take the medication with a full glass of water, and at least one hour before or two hours after meals.

Pregnancy Use

Diclobene retard should not be used during pregnancy, except if clearly necessary. If used, regular monitoring of the baby's condition is advised.

Lactation Use

Diclobene retard should not be used while breastfeeding, as it may pass into breast milk and affect the baby.

Acute Overdose

An overdose of diclofenac can be serious; symptoms may include nausea, vomiting, stomach pain, and dizziness. If an overdose is suspected, contact a doctor or poison control center immediately.

Contraindication

Diclobene retard should not be used in patients with known hypersensitivity to it, or to other NSAIDs. In addition, it should not be used in patients with bleeding disorders, or in patients with a history of ulcer or stomach bleeding.